Read our 2024 Annual Report

Current Investments

ARMR is developing hemorrhage control systems to increase the survivability of traumatic injuries.
Astek is developing a rapid-testing device for one-hour UTI detection & antibiotic sensitivity indication.
Common Curriculum is a lesson planning and sharing tool for teachers and school districts to meet Common Core standards.
CoolTech’s transnasal cooling technology provides non-invasive fever control and neuroprotection for acute healthcare patients.
Cove is developing non-viral, nanoparticle gene therapies for monogenic ophthalmic and neuromuscular disorders.
eNeura’s portable, non-invasive transcranial device uses magnetic pulsing to treat and prevent migraines.
Gliknik develops innovative biologics and therapies to fight cancer, disease, and autoimmune disorders.
Irazu’s vaccine platform is versatile and cost-effective, with broad applications in cancer treatment.
LPPFusion is developing a dense plasma focus fusion generator to produce an economical, clean, and inexhaustible source of electric energy.
LifeSprout is developing the next generation of synthetic soft tissue material for cosmetic and reconstructive surgery.
Linshom developed a respiratory monitor that provides continuous, uninterrupted, critical respiratory information through innovative monitoring technology.
Longeviti is pioneering innovative solutions and implantable technologies for complex brain surgeries.
Marigold (formerly Sunrise) is a mental health app providing group therapy and peer support in a safe and scalable manner.
Marinalife delivers tools, resources, and tech-enabled solutions for the boating community.
Materic’s 3D fibrous BioPaper scaffold offers researchers new possibilities for medical device development.
Minnowtech develops precision aquaculture technologies to maximize aquafarmers’ cultivation efforts.
MF Fire is leveraging advanced combustion science to engineer the world’s cleanest wood stove technology.
NextStep combines robotics and information technology to prevent falls and fall-related injuries caused by foot drop.
NAWEC’s pulse jet engine delivers fuel efficiency, vibration control, and noise reduction without any moving parts.
Noxilizer provides room temperature nitrogen dioxide sterilization technology and equipment.
Oncospace’s cloud-based radiation planning software leverages a rich database of information to provide optimal treatment plans.
OTEC harnesses solar energy from tropical oceans to deliver electricity to utility grids.
Pixelligent delivers next-generation optical materials for displays and applications, including solid-state lighting.
The Propel Baltimore Funds provide early-stage, technology-focused venture capital to Baltimore entrepreneurs.
ReGelTec is developing minimally invasive spinal implants for lower back pain and degenerative disc disease.
SIMPLi is ethically sourcing single-origin ingredients to transform the food industry into a sustainable and fair marketplace.
Sisu is building a pipeline to strengthen global health systems through medical device commercialization.
Sonavex uses cutting-edge imaging technology to provide visualization of critical data directly at the surgical site.
Sonosa is transforming the pathway to diagnosing, treating, and managing Obstructive Sleep Apnea.
TRI’s gasification technology enables state-of-the-art conversion of waste into green fuels, chemicals, and renewable energy.
VM is developing non-invasive devices for dynamic assessment of blood flow and vascular status.
Vita Therapeutics is harnessing the power of genetics to develop cellular therapies.
Vixiar Medical develops non-invasive devices and systems for monitoring cardiopulmonary diseases.

Past Investments – Baltimore Successes

Breethe’s OXY-1 System aims to improve outcomes and quality of life for patients who suffer from acute and chronic lung failure.
Factory Four’s Manufacturing Execution System optimizes business operations and decreases product lead time.
Graybug’s proprietary drugs treat age-related macular degeneration, diabetic retinopathy, corneal graft rejection, and glaucoma.
HARPOON Medical is pioneering a beating-heart repair procedure for degenerative mitral regurgitation.
Network for Good’s fundraising platform supports charitable giving through customized web pages and mobile applications.
Oasis Marinas offers full-service marina management, consulting services, and slip booking through the Snag-a-Slip cloud-based system.
Paice is at the forefront of hybrid-vehicle technology to improve performance, maximize fuel efficiency, and reduce emissions.
PGDx is developing a portfolio of regulated tissue-based and liquid biopsy genomic products for cancer patients and laboratories worldwide.
Spine Align’s platform technology is focused on transforming spinal and orthopedic surgeries through real-time 3D measurements.